In this work have been investigated the transport properties of superconducting hybrid systems made with semiconducting InAs-NWs - Aluminium and semiconducting InAs-NWs-YBCO. Mixing bottom-up and top-down nanofabrication approaches Josephson junctions in non-suspended and suspended design have been built. InAs-NWs have been positioned by random and assisted technique. A comparison of the transport properties for suspended and non-suspended architectures show that the coupling between the substrate and the normal region of the junction does not affect the transport properties of these devices. The nanotechnology platform developed for suspended LTS junctions has represented the starting point for the integration between YBCO and the semiconducting InAs-NWS. Several efforts have been accomplished and many design of the structures have been developed. The achievements in the nanofabrication reported in the present work can be considered as very encouraging in the direction of the realization of the Josephson field effect transistor with HTS/InAs-NW/HTS.